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| Thoughts and opinions on antidepressants Posted: 9/17/2009 11:51:44 AM | Whose crazy idea was it to say everyone should be happy and not depressed all the time? I'm gonna go put on a limb and say this:
The chemical imbalance is a reflection of whatever is wrong or missing or inadequate in one's life, it's not the cause (Perhaps in a small minority there may really be an imbalance). How many popular, successful, attractive, wealthy, healthy people, who get enough sex and exercise, need anti-depressants on a permanent basis? Don't bullsh!t me and say loads, or “I know such and such who has everything and still need pills”.
There is an interesting study I came across that measured serotonin in non-human primates (I forgot which exact species). High status males have plenty of the stuff, however when they are usurped and become low status males they suddenly have a “Chemical imbalance”.
In any case, the effects of anti-depressants often wear off when taken on a long term basis (over 6 weeks). In fairness some people do say anti-depressants saved their life but would ALL of them they really need them permanently if they had everything they want in life? | |
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Sannia
| Joined: 9/11/2009 Msg: 77 | |
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| Thoughts and opinions on antidepressants Posted: 9/17/2009 12:21:49 PM | ^^^ So called educated professionals are labelling people as "broken" just because those "broken" people aren't having their needs fulfilled. This is one of the reasons that I'm sceptical in taking psychiatry seriously. | |
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| Thoughts and opinions on antidepressants Posted: 9/17/2009 2:19:06 PM | | Psychiatry and psychology should be taken seriously. They are by no means a science as we have not even come close to figuring out why we do the things we do, why we react certain ways, and what causes depression. The problem is that psychiatrists are also medical doctors. Now every M.D. I have ever come across is interested in as seeing as many patients in a day as quickly as he/she can because that is how doctors make the big bucks. Unfortuneatly this mentality has spread into the psychological field of medicine."Psychiatrist" Your feeling sad, lathargic, no desire to get out of the house? Here take these pills one every morning and things should get better. If they dont call me and we will switch you to a diffrrent pill NEXT! Alot of these doctors have become way to enamored with all the money they could make instead of what I hope was part of the original intent which was to help people or progress knowledge of a disease. The greed of doctors and the billions of dollers involved in these medicines because of the pharmocutical industry is the primary reason that antidepressants are being so widely and probably to quickly prescribed. | |
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| Thoughts and opinions on antidepressants Posted: 9/17/2009 2:45:24 PM | I used to believe that anti-depressants were very necessary and great medications for depression till I took them myself and lived through my family taking several different types. Anti-depressants DO NOT cure depression and they can have way too many side effects to be considered necessary or safe to use. I've had three people suicidal on these medications. Not to mention the agitation, the lethargy, the confusion, the weight gain, the lack of sexual libido, etc. All in all I give anti-depressants a "D" for dangerous.
I also feel that other drugs might cause many depressions such as these below:
"Various drugs including antihypertensives, anxiolytics, antibiotics, antidepressants, corticosteroids, choline, indomethacin, levodopa, metronidazole, neuroleptics, oral contraceptives, sulphonamides and physostigmine have been reported to produce depression as a side effect. Clinically, these drug-induced depressions may go unnoticed and thus create therapeutic problems. Although causal relationship is difficult to establish, depression occurring during the course of drug treatment needs an evaluation of all the medications that the patient has been receiving. We believe that postpsychotic depressions include three types of depression: pendular depression--primarily disease related; chronic depression--primarily environment related, and amine-depletion depression--drug related. Thus, drug-induced depressions constitute a subgroup of postpsychotic depression. Clinically, it is essential to carefully monitor patients receiving drugs known to produce depression. Thus, prompt recognition of the drug-induced depressions may assist in initiating proper therapeutic measures." (this is a great article)
Patten SB, Love EJ. Drug-induced depression. Psychotherapy and psychosomatics. 1997;66(2):63-73.
"Certain drugs may contribute to the etiology of depressive symptoms and depressive disorders.... Corticosteroids, certain calcium channel blockers and digoxin have been associated with depression by replicated, well conducted studies. Psychostimulant withdrawal is also associated with prominent depressive symptoms. Preliminary evidence suggests that antihyperlipidemic agents, angiotensin converting enzyme inhibitors, sedative hypnotics, psychostimulants and certain hormonal agents may also cause depression.... Conclusions: A small, but growing, literature confirms that certain drug exposures can contribute to the biopsychosocial etiology of depressive symptoms and disorders. Current beliefs and diagnostic conventions classify drug-induced depression into a distinct category (Substance-Induced Mood Disorder): but this approach is not specifically supported by the existing literature."
Rollof J, Vinge E. Neurologic adverse effects during concomitant treatment with ciprofloxacin, NSAIDS, and chloroquine: possible drug interaction. Ann Pharmacother. 1993 Sep;27(9):1058-9.
"A 68-year-old woman who was receiving chronic treatment with NSAIDs and chloroquine developed dizziness, anxiety, and tremors when ciprofloxacin 500 mg twice daily was begun for Salmonella osteitis. When she discontinued the antirheumatic treatment, there was a prompt relief of symptoms."
Voth AJ. Possible association between metronidazole and agitated depression. Can Med Assoc J. 1969 June 7; 100(21): 1012–1013.
"Within two days of beginning this treatment the woman developed a severe agitated depression. She called me up at night complaining of insomnia, extreme restlessness, agitation and severe depressive feelings with uncontrollable weeping spells. She blamed the medication for her condition because she had never experienced such a reaction before. I doubted this association but suggested that she stop the medication for two days. She returned to her normal self within 24 hours. She had no previous record of emotional or psychiatric upset and the only other medication she was using was Norinyl-1 which she continued to take. I would be interested to know if other physicians have had similar experiences with metronidazole."
Andrea Runyan studied math at Stanford University. She now writes about Lyme disease, health, alternative medicine, the Diamond Approach, and the Enneagram.
http://www.americanchronicle.com/articles/view/102114
I had a relative take a new medication for quitting smoking recently who became very agitated, anxious, suicidal and sick at their stomach. It was the medication. As soon as they stopped it they were fine. | |
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 12:34:32 PM |
how did we survive the last 20 000 years and more without them ?
Usually, by dying before our 30th birthday. Many didn't make to their 1st birthday.
Do these drugs make us as happy as a simple dog? Or as obedient?
READ! Libraries are diminishing slowly - READ! and discover get off this web said the spider
I find it hysterical that you advise others to read while demonstrating such ignorance about prescriptions drugs. Even those who oppose the widespread use of SSRI's know that they dont make people obedient.
I know one person who should take your advice, get off the web, and READ about SSRI's, their effects, and the REAL RISKS of taking an SSRI. | |
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 3:34:32 PM | Clinical depression is not feeling sad. It is where traumatic events or an extreme state of mind has caused measurable physiological effects. A patient may feel quite content when they start hallucinating about stalking daemons for apparently no reason. When doctors talk about chemical imbalance they're talking about your muscles and organs doing things they shouldn't be doing. It is a qualified medical illness due to its physiological nature. You really should look up some extreme case studies published since the 1930's. Indeed medication is designed to lessen the detriment of symptoms so that the core issues may be resolved with less complicating distraction. They are not a cure. But there are cases where the state maybe relatively untreatable and sustained medication is the only recourse left with which to provide any quality of life.
They tried the tough love approach in the Middle Ages and it didn't work out. In fact when finally faced with the full scope of possible symptoms in extreme cases the same people who propose the tough love approach tend to head directly to the opposite extreme and assume things like spiritual possession, especially if they have any religious or superstitious leanings. At best they will consider the patient totally aberrant by course or heritage, which amounts to the same thing. These attitudes continue to this day, the most recent widely publicised case being in Belarus 2006 iirc, in which as typical the patient was murdered during a commuity based ritual. In other words the people who think the symptoms of clinical depression and related illnesses are delusional tend to be the most freaked by actually seeing them at work on the body. But imagine what the patient is going through in a developed society, knowing rational people are totally freaked out by the reality of it and simple ones would do them harm for it.
The medical approach has been frought with the development of low impact drugs with good tranquilizer effects which still allow cognisant behaviour. Left untreated clinical depression symptoms can drive serious and distressing conditions like manic hysteria and paranoid schizophrenia or other psychosis, with quite some physical detriment directly associated. At this point it is not entirely removed from a dangerous non-infectious disease, indeed being driven insane by medical disease was not entirely uncommon in ye olde times, which is why sanitoriums were built. Both are related to brain chemistry.
The assumption that clinical depression is normal behaviour is very ignorant and discounts a couple of centuries of medical research to the contrary. Assuming the entire medical profession are not a modern Inquisition of evil liars with financial and political agendas, the statistics of serious mental illness are significant of a serious social issue which shouldn't be passed off with some hand waving, which is probably why there are so many in the first place.
Essentially it might be easiest to just take a democratic approach to it all if you're not medically qualified to promote or deny particular treatment. If someone says something is distressing them, they're probably telling the truth. If they say it is physical, seeing a physician is probably the best advice. And if they're being treated for physical symptoms as is invariably the case when medication of any sort are prescribed (the days of surreptitiously prescribing valium for husbands to quieten their wives over a little infidelity are long gone), then it is a guarantee that physical symptoms are being treated and the patient deserves a little sympathy instead of contempt.
I mean how greedy for attention must you be to steal the thunder of ill people. You want to bully some primary schoolers while you're at it? Fair enough nobody likes a liar, but you should clearly establish that a claimant to mental illness of any sort is exaggerating before you land the hammer of backyard justice and outright ignorance on their heads.
Clinical depression is no party, and if curing it was as simple as just "getting over yourself" then wow, you've just solved a major social and medical issue and thousands can thank you for healing them like Jesus. Strange that the qualified experts are finding it a little harder to deal with.
Finally attempts to discredit the medical profession in the hope to substantiate an irrational conclusion is no argument. The simple fact is brain chemistry and the very functioning of the brain is not an exact science, neurosurgeons are confounded regularly. When assigning anti-depressants one of the main focal points is finding the right medication by trial and error. What works well to treat one person's symptoms may give dramatic side effects treating the same symptoms for another patient. This may be due to the individual variation which is common to brain function.
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 4:46:41 PM | | I think that the study of the brain is almost the last frontier in clinical exploration of how humans function or not . I kmow they have now something even better than an MRI which shows in colour images of depressed and non depressed brains . As a left hander , I've always been interested in why my brain apparently drew from the opposite lobe to a right handers . This area of exploration is more important than exploring the moon . | |
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 5:45:14 PM | ^^^ vanaheim
What proof do you have that some people are not depressed due to having inadequate lives, and that human beings did NOT evolve the adaptive motivational behaviour as a deterrent to failing to for-fill our needs. Again, there may be a minority who really do have genetic programming that makes them susceptible to these states and even more difficult for them to pull out of these states.
Edit: nevaagin - Indeed our brain and bodies are the final frontier of unknowns, oh that and space exploration :) . | |
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 6:19:41 PM |
What I found in that particular situation, for me, was that allowing myself to feel what I felt, and to deal with those feelings, and painful and paralyzing as they were, enabled me to get through them, and my grief. I also noticed that in my grief group, people taking those pills drugged away their feelings - and ended up mired for years in unresolved issues.
It's always been my belief that "feel good" chemicals do nothing whatsoever except deal with the symptoms and nothing for the cause. They only mask the problems and do nothing about dealing with them. I think doctors rely on "feel good" pills far too much and specially with young people and kids that are "unruly" and "acting out". There are sound reasons kids do this and to drug them up is, IMHO, plain wrong.
Medical science is on in it's infancy on the issue of the mind-body connection. They're only beginning to understand the link. I believe the dis-ease can CAUSE a chemical imbalance and treating those with drugs is wrong. As the poster above pointed out, drugging herself would not allow those feelings of sadness and loss to come to the surface would have merely pushed them to the subconscious and that's where the damage is done. Better to face those feelings and learning to understand and deal with them is far more productive than simply covering up the symptoms to make one "feel better". Feeling better and being better are two different things. | |
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 6:25:10 PM | | Bluesman, ultimately the Doctor can't do anything to solve the underlying problem, that's entirely in your own power. However, while you're resolving the issues yourself, AD can be a great help. I would give a personal example here but I'd rather not. For me, there were two negatives and one positive. The positive was an increase in self-confidence which enabled me to function in the areas I was previously having difficulty functioning in. The negatives were the withdrawl symptoms ("head-shocks" with Lustral/Zoloft) and the fact that I didn't feel anything. In the end, because of the latter, I stopped taking them but by that time the underlying problems were gone. | |
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| Thoughts and opinions on antidepressants Posted: 9/18/2009 6:57:07 PM | | That's exactly why I said that pills alone are NOT the answer. Their temporary use WHILE in therapy may be necessary for a short time but not a lifetime crutch because, you're right, YOU must ultimately solve your own problems but you can't do that with drugs alone. | |
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| Thoughts and opinions on antidepressants Posted: 9/20/2009 11:19:18 AM | Vanaheim
Thank you for your thoughtful, empathetic, and concise description of clinical depression.
In order for an individual to suffer from this debilitating dis-ease, both a genetic and an environmental component must be present. The full horror and pain associated with this type of sickness can not be expressed in a mere posting on a dating site.
It is true that many of the SSRI's have side effects that are unpleasant. However, telling someone to buck up or live through the physical pain and desire to end that pain by suicide is akin to throwing a towel to someone in the midst of a thunderstorm.
And the scientific community in the last 10 years has made great strides in comprehending the body's, and perhaps the universe's, most complex networking system. The 1990's were labeled the decade of the brain. And with the advent of the fMRI as well as other imaging techniques, (PET scans, CT Scans, Electron Photomicrography) can explore the brain without waiting for cadavers to do research.
I know that the side effects of the medications on the market can be debilitating. But weighed against the benefits, they seem almost minimal. A great majority of psychiatrists and psychologists are interested in alleviating human suffering. There will probably come a time when not only certain synapses on the axons of neurons can be blocked or stimulated at will, but when we will be able to target only certain neurons in specific locations of the brain to rectify the neurotransmitter sparsity.
I am very grateful to the man who invented Prozac (Fluoxetine). | |
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| Thoughts and opinions on antidepressants Posted: 9/20/2009 11:43:45 AM | Don't worry...be happy! A pill for everything! Pharmaceuticals are the wave of the future! Get them prescription pads out docs! And a BIG pen! | |
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| Thoughts and opinions on antidepressants Posted: 9/20/2009 4:38:47 PM | I think like most drugs, there's a hasty tendency to dole them out among many doctors. Like other drugs, sure, chances are it will bring an immediate positive upside, which is why people will swear by it and claim "you don't know!" to others who haven't been in their shoes exactly... whether it be depression or anything else.
Obviously the pharm companies want to sell as many as possible -- that IS going to affect doling them out, and make it more hasty, no matter what anti-depressant lovers will say.
I would say the best thing to do is to use official anti-depressants as a last resort, and if/when doing so, targeting a short-term route. Adjusting your diet can have huge physical and mental effects, in a negative or positive direction. Same with intense exercise (yes, mentally -- bigtime). Of course, a doctor is not a law-enforcement-personal-trainer, so the obvious easy step is to have you pop a pill. But in doing so, of course, more people are going to take the easy route -- which of course can be a just-fine route for some, an okay-route but unnecessary and not-the-best-option for others, and sometimes just not a good route for others. | |
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| Thoughts and opinions on antidepressants Posted: 9/20/2009 8:17:23 PM | Some facts I know about antidepressants: * Antidepressants are extremely hazardous and detrimental to health and the immune system. * They don't cure the illness, they just mask symptoms. * There is no real test that shows a chemical imbalance in brain chemistry. This is just something used by the pharm industry to push pills.
There is something known as LD50 in pharmacology. This is lethal dose 50. Essentially what this tells you is the lethality of a drug. They come up with the LD50 of a drug compound by giving lab rats or college students the maximum effective dose until half of the population dies. Here are LD50 profiles for some known drugs:
* Prozac- very dangerous - 10 times the effective dose can kill you, or ten pills * Marijuana- very safe - Virtually harmless * Mushrooms- very safe - 1000 times the effective dose can kill you, you would have to eat your own body weight. * MDMA (extacy)- very dangerous - 10 times the effective dose can kill you, or ten pills * Zyprexa- very dangerous - 10 times the effective dose can kill you, or ten pills * LSD (acid)- very safe - Virtually harmless | |
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| Thoughts and opinions on antidepressants Posted: 9/20/2009 11:14:27 PM |
What proof do you have that some people are not depressed due to having inadequate lives, and that human beings did NOT evolve the adaptive motivational behaviour as a deterrent to failing to for-fill our needs. Again, there may be a minority who really do have genetic programming that makes them susceptible to these states and even more difficult for them to pull out of these states.
I was discussing published findings. Your question is confusing, could you clarify perhaps giving example? Clinical case study works best but hypothesis will do. Most tenders I've been reading were sourced via references given in articles at the Science Daily website, if that helps for further information regarding the subject.
What it appears to me is that you've confused "feeling sad or inadequate" with the distinctly medical, biochemical illness known as clinical depression, which is an entirely different kettle of fish. I have no doubt that in many cases of mundane "sadness or frustration" the subject attempts to misrepresent themselves as clinically depressed for reasons of emotional dependency and attention seeking, however the genuine sufferers of mental illness should not be tarred with the same brush just because this is a viable social and economic concern.
And still there are no identified genetic descriptors of most psychiatric conditions, although they are medical (biophysical) in nature. It appears more likely the human physiology adapts to sustained psychological conditioning than it does the other way around, although in either case this fosters more serious psychiatric conditions.
There is no real test that shows a chemical imbalance in brain chemistry. This is just something used by the pharm industry to push pills. Feller, it's called a fluid biopsy.
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 1:19:09 AM | “I was discussing published findings. Your question is confusing, could you clarify perhaps giving example? Clinical case study works best but hypothesis will do. Most tenders I've been reading were sourced via references given in articles at the Science Daily website, if that helps for further information regarding the subject.” Clarify? There is no need, the question I asked is fine, please re-read it. Is depression an adaptive trait or not?
“with the distinctly medical, biochemical illness known as clinical depression” Circular argument to my question, you’re using the premise to prove that it is indeed an illness as oppose to an adaptive trait. No I am not confusing sadness and depression. You can answer whether either sadness or depression are adaptive traits or illnesses. | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 1:26:56 AM | Just a clarification:
Serotonin is a neurotransmitter (NT). It is a compound that exists in the synaptic vesicles in your nerves, as are dopamine and acetylcholine.
When a NT is released from the synapse it keeps transmitting the signal to the next nerve to initiate a signal (action potential) along that nerve. So that you don't feel everything for the rest of your life, these NTs are degraded or re-uptaken into the synaptic vesicles after they've done their job of transmitting the signal.
Of course different NTs are more prevalent in different parts of the nervous system. One part of your nervous system is the one that controls pain: the analgesia system that inhibits pain signals at the spinal cord level. Several NTs are involved, but especially enkephalin and serotonin. (This is just one place serotonin is active).
So if you take a drug that either acts like serotonin or stops it's re-uptake, you are increasing the amount that the serotonin acts.
LSD is a molecule that has a similar shape to that of the serotonin molecule. It's shape is close enough that the receptors for serotonin in the synapses react to LSD as well.
Where SSRIs stop the re-uptake of the NT, LSD provides more of the NT. However your nervous system did not evolve a way to re-uptake or degrade LSD quickly, so the drug lasts several hours.
I just wanted to say that SSRIs are, in my opinion, LSD light. I agree with Bright1 that they are useful as a bridge to wellness. They should not be considered a substitute for it.
P.S. Prolonged LSD use degrades the system it acts upon. Like cocaine and nicotine it changes the areas of the nervous system upon which it acts. People lose their analgesic and tactile senses and sometimes balance and fine motor and speech control from prolonged LSD use. There are other less-well documented negative effects too. It is decidedly not harmless. | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 1:17:09 PM |
P.S. Prolonged LSD use degrades the system it acts upon. Like cocaine and nicotine it changes the areas of the nervous system upon which it acts. People lose their analgesic and tactile senses and sometimes balance and fine motor and speech control from prolonged LSD use. There are other less-well documented negative effects too. It is decidedly not harmless.
Yes, but you would have to consume a huge amount of LSD throughout your lifetime. 1000's of hits, and you would still survive. Old age would most likely impair you with loss of motor control and alzheimer's before the LSD has a chance to touch you in a negative way. So all in all, it's virtually harmless.
Try doing that with an anti-depressant or cocaine or heroin. | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 1:27:18 PM |
Yes, but you would have to consume a huge amount of LSD throughout your lifetime. 1000's of hits, and you would still survive. Old age would most likely impair you with loss of motor control and alzheimer's before the LSD has a chance to touch you in a negative way. So all in all, it's virtually harmless. I'm feeling a little Google-lazy, can you point me to any 30+ year long studies that have shown LSD to be harmless in humans? | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 2:15:58 PM | okcupid, your amorphous contention is not going to be won by personal argumentation. Look up the published findings and then come back commited to solid statements on the subject with references. Use the Science Daily website as a resource. Give references of medical papers for your basis to challenge the published findings of the medical research communities with some kind of ridiculously generalised evolutionary philosophy you've invented.
When you don't have any qualified backing for an abstract, the wall of published findings and existing data are not a circular argument against you. They are an impenetrable one rather. I am merely reiterating scientific papers, so I am simply not arguing in a circular fashion or any other. I am relating published findings. The onus is on you to challenge the medical community with demonstrable findings of reproducible experimentation and observation in nature, satisfied by the course of peer review that certain celebrated medical illness are in fact evolutionary adaptation.
Because until you do, what it is called is simple bigotry regardless how you've self justified it. By your minoritisation of the mental health facility, which I might add is a celebrated major public welfare concern. Hand waving with concoction is not any scientific approach no matter how articulated. Stick to the published findings, use those for personal ethic. Not just whatever you feel like thinking up to suit your own predisposed behavioural routines regarding others. | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 2:54:49 PM |
I'm feeling a little Google-lazy, can you point me to any 30+ year long studies that have shown LSD to be harmless in humans?
More money has been spent trying to find something wrong with cannabis than any other vegetable material in human history, and what they've come up with is so pathetically thin that it amounts to a clean bill of health for this stuff. Cannabis is not a health problem; the problem is that it promotes social values and attitudes which are unwelcome in capitalist’s marketplace societies. It's just that simple.
A drug like coffee, with a horrendous health profile compared to cannabis, is completely welcome in the marketplace, in the home, in the lifestyle of modern people. We value certain states of mind, and we fear others...that's getting off the point, but....
LSD is a similar story. LSD research was terminated in the 70's. LSD was never given a fair chance to be studied with a purpose of educating the community on safe and responsible usage. I never said that LSD was completely benign. I said that it is virtually harmless. Because let's be realistic, anything in excessive amounts can be potentially dangerous. I was merely comparing LSD to anti-depressants. You're going to believe what you want to believe regardless of what you read or hear. | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 7:54:14 PM | Marijuana's active ingredient - THC - is endogenous to humans. We make it ourselves. I agree it is harmless. You can not OD on ganja. You don't have to smoke it, so the lung-cancer argument is moot. I love marijuana, even though I quit it after being an afficionado and grower of super dank nugs for 25 years.
If you do LSD for a few years every week you will be a stumbling drooling husk of a person. I've seen it happen. I don't mean to split hairs, I just don't want to let a danger go unnoticed here. Respect to you NLTB. | |
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| Thoughts and opinions on antidepressants Posted: 9/21/2009 9:27:44 PM | | There are different types of anti-depressant ...... all with the aim of kick starting the brain into producing enough seratonin and there are a few other hormones involved that need to be in better supply for the brain . They are specifically for the people whose brains have failed for whatever reason , including genetic predisposition to supply the natural 'happy hormones ' . People who really believe you can rescue an emotionally drowning person by making them go for long runs are just repeating the age old 'pull yourself together' adage ........... and there were many victims of this approach . You must have medical advice and be patient sometimes as each different type of anti-depressant can work quicker with some people than with others . It's sort of horses for courses . The main thing to try and keep in mind is that you are not abnormal ... the percentage of depressed people is quite high and actually you are in good company as it is people who feel things deeply and are more sensitive to emotional stress who are your companions . | |
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