Hopefully we are the last generation to experience such barbaric treatment
just so big pharma can make a buck.
Thoughts ?

I think the OP has an agenda

the OP has little knowledge or understanding of neuroscience.

I think that most people don't know neuroreceptors even exist, let alone any two particular receptors,

let alone any two particular receptors,

outrage over not being informed of a particular two out of God knows how many known is kind of childish

And I think that if OP were a regular listener to NPR he would have learned of the existence of said receptors years ago

Marijuana ineffective as an Alzheimer's treatment: UBC-Vancouver Coastal Health research

The benefits of marijuana in tempering or reversing the effects of Alzheimer's disease have been challenged in a new study by researchers at the University of British Columbia and Vancouver Coastal Health Research Institute.

The findings, published in the current issue of the journal Current Alzheimer Research, could lower expectations about the benefits of medical marijuana in combating various cognitive diseases and help redirect future research to more promising therapeutics.

Previous studies using animal models showed that HU210, a synthetic form of the compounds found in marijuana, reduced the toxicity of plaques and promoted the growth of new neurons. Those studies used rats carrying amyloid protein, the toxin that forms plaques in the brains of Alzheimer's victims.

The new study, led by Dr. Weihong Song, Canada Research Chair in Alzheimer's Disease and a professor of psychiatry in the UBC Faculty of Medicine, was the first to test those findings using mice carrying human genetic mutations that cause Alzheimer's disease -- widely considered to be a more accurate model for the disease in humans.

"As scientists, we begin every study hoping to be able to confirm beneficial effects of potential therapies, and we hoped to confirm this for the use of medical marijuana in treating Alzheimer's disease," says Song, a member of the Brain Research Centre at UBC and VCH Research Institute and Director of Townsend Family Laboratories at UBC.

"But we didn't see any benefit at all. Instead, our study pointed to some detrimental effects."

Over a period of several weeks, some of the Alzheimer's-afflicted mice were given varying doses of HU210 -- also known as cannabinoids -- which is 100 to 800 times more potent than the marijuana compounds. Their memory was then tested.

The mice treated with HU210 did no better than untreated mice, with those given low doses of HU210 performing the worst. The researchers also found that HU210-treated mice had just as much plaque formation and the same density of neurons as the control group. The group given higher doses actually had fewer brain cells.

"Our study shows that HU210 has no biological or behavioural effect on the established Alzheimer's disease model," says Song, the Jack Brown and Family Professor and Chair in Alzheimer's Disease. "More studies should be done before we place much hope in marijuana's benefits for Alzheimer's patients."

Alzheimer's disease is a neurodegenerative disorder characterized by progressive cognitive deterioration and is the most common form of dementia.

The Alzheimer Society of Canada estimates that the disease affects close to 300,000 Canadians and accounts for two-thirds of all cases of dementia. Approximately $5.5 billion per year is spent caring for persons with Alzheimer's and related dementias in Canada. By 2031, about 750,000 Canadians will suffer from Alzheimer's and related dementias.

The Alzheimer's Association in the U.S. estimates there are approximately 500,000 Americans younger than 65 with Alzheimer's or other dementia.

The research was supported by the Canadian Institutes of Health Research, the Jack Brown and Family Alzheimer's Research Foundation, the Michael Smith Foundation for Health Research and a donation from the David Townsend Family.

Townsend Family Laboratories was established at The University of British Columbia with a donation of $7.5 million from the David Townsend Family. The research centre is dedicated to integrating the basic and clinical research for finding the underlying mechanism and novel diagnostic biomarkers for Alzheimer's Disease and developing interventions to prevent and treat this devastating disease.

The UBC Faculty of Medicine provides innovative programs in the health and life sciences, teaching students at the undergraduate, graduate and postgraduate levels, and generates more than $200 million in research funding each year. In 2007/08, out of the total UBC research endeavour, 53 per cent, or $247 million, came from academic and clinical teams in the Faculty of Medicine. For more information, visit www.med.ubc.ca.

The Brain Research Centre comprises more than 200 investigators with multidisciplinary expertise in neuroscience research ranging from the test tube, to the bedside, to industrial spin-offs. The centre is a partnership of UBC and VCH Research Institute. For more information, visit www.brain.ubc.ca.

Vancouver Coastal Health Research Institute (VCHRI) is the research body of Vancouver Coastal Health Authority, which includes BC's largest academic and teaching health sciences centres: VGH, UBC Hospital, and GF Strong Rehabilitation Centre. In academic partnership with the University of British Columbia, VCHRI brings innovation and discovery to patient care, advancing healthier lives in healthy communities across British Columbia, Canada, and beyond. www.vchri.ca.

Link:

http://www.ubc.ca[ quote]

The thing with this testing is that they didnt use real cannabis . They used HU210 which is 100 to 800 times more potent then cannabis itself.
{quote] Facts: HU210, sold commercially as Spice, is a powerful full agonist at receptor CB1. Cannabis is a partial weak agonist. To help explain this graphically, picture an adult African Lion, then picture a fluffy little kitten sitting pretty.
In case anyone was wondering, mice do not get Alzheimer's. And lab rats given Thalidomide don't get birth defects.

obesity might never have had a chance

linical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

If you want to add a study or a case report please click here. Studies and case reports will be checked by the IACM before publication in this database. Please do not forget to enter your e-mail address in the field "address of author" for any request.

[Back to Overview] [IACM Homepage]
Title Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory.
Author(s) Foltin RW, Fischman MW, Byrne MF.
Journal, Volume, Issue Appetite 1988;11(1):1-14.
Major outcome(s) Increases in body weight during periods of active marijuana smoking were greater than predicted by caloric intake alone.
Indication Appetite loss/weight loss Abstract
Medication Cannabis

Six adult male research volunteers, in two groups of three subjects each, lived in a residential laboratory for 13 days. All contact with the experimenter was through a networked computer system and subjects’ behaviors, including food intake, were continuously reported. During the first part of the day , subjects remained in their private rooms doing planned work activities, and during the remainder of the day, they were allowed to socialize. Two cigarettes containing active marijuana (2-3% Delta-9-THC) or placebo were smoked during both the private work period and the period of access to social activities. Smoked active marijuana significantly increased total daily caloric intake by 40%. Increased food intake was evident during both private and social periods. The increase in caloric intake was due to an increased consumption of snack foods as a consequence of an increase in the number of snacking occasions. There was no significant change in caloric consumption during meals. The principal increase within the category of snack foods was in the intake of sweet solid items, e.g., candy bars, compared to sweet fluid, e.g., soda, or savory solid items, e.g., potato chips. Increases in body weight during periods of active marijuana smoking were greater than predicted by caloric intake alone.

Manitoba Harvest Improves Hemp Oil Packaging


2010-02-09 - Manitoba Harvest

(Winnipeg, Manitoba – February 9, 2010) – People throughout the world are becoming aware that the choices they make regarding culinary oils in their diet can have a profound impact on their health. Omega-rich hemp oil is one of the emerging nutritious oils being sought out by health-minded consumers, as well as foodies seeking flavorful oils that add an interesting flavor, color and texture to recipes. Manitoba Harvest Hemp Foods & Oils™ has announced that they have improved their hemp oil packaging, which features a convenient no-drip spout.

Manitoba Harvest Hemp Oil has a rich nutty flavor and is a nutritious addition to healthy recipes such as salad dressings, soups, sauces, juices and smoothies. You can substitute hemp oil for virtually any other oil in recipes that are not heated above 350º F. Hemp oil can also be drizzled on top of cooked foods for added taste and nutrition. A tasty hemp oil recipe for Hempini Dressing is included below, and more can be found at www.manitobaharvest.com/recipes .

“There are six key advantages that hemp oil has over other oils and EFA sources,” says company President and co-founder Mike Fata. “Hemp oil offers the highest level of EFAs of any vegetable source, provides optimal balance between omega-6 and omega-3 EFAs, is a rare source of GLA, contains many other key nutrients beyond the EFAs, has a delicious flavor and culinary versatility, and is derived from sustainable agriculture,” notes Fata. “Many people are seeking to gain their EFAs from delicious functional foods instead of supplement pills,” add Fata.

A summary of hemp seed health and nutrition research presented to the Canadian Hemp Trade Alliance
(www.hemptrade.ca ) at their annual conference in November 2009 by Kelly Fitzpatrick, M Sc., demonstrates the emerging science behind this superfood. The key points backed by referenced research in her report are:

- Hemp oil contains an extremely healthy fatty acid profile with the highest total level of important essential fatty acids: 55% linolenic acid (LA); and 19% alpha linolenic acid (ALA);

- Hemp oil is a rare plant source of the vital omega-6 EFA gamma linolenic acid (GLA) and another unique omega- fatty acid called stearidonic acid (SDA);

- Hemp oil is very low in saturated fats;

- Omega-6 and omega 3 EFAs work synergistically at the cellular level to ensure effective metabolism. Hemp oil has a 3:1 ratio – the oil closest to an ideal recommended omega 6 and 3 ratio;

- Hemp oil contains antioxidants including natural Vitamin E (tocopherols) at higher levels than other oils;

- Hemp seeds are rich in phosphorus, potassium, magnesium and calcium, and are a very good source of important B vitamins including pantothenic acid, niacin and Vitamins B1, B2 and B6; and

- A variety of phytosterols are found in hemp oil, these substances have a positive effect on blood lipids.

“In addition to its high concentration of omega-3, hemp oil is a rare source of Gamma Linolenic Acid (GLA), which is a unique and extremely important Omega-6,” notes Meghan Atkinson CN, a certified nutritionist based in Los Angeles, California. Obtaining GLA in the diet can be challenging. “Other than hemp, there are only 3 significant natural sources of GLA - Evening Primrose, Borage, and Black Courant -and unlike hemp, none of the others are a whole food source with a wide variety of culinary functions,” adds Atkinson. Hemp Oil contains 420mg of GLA in one tablespoon.

To create Manitoba Harvest Hemp Oil, hemp seeds are cold pressed to ensure that valuable enzymes are not destroyed and nutrients such as chlorophyll and vitamin E remain intact. Unlike conventional vegetable oil refining, the “FRESH PRESSED™” process used by Manitoba Harvest does not subject the oil to poisonous chemicals or destructive heat. Manitoba Harvest Hemp Oil is packed in light-resistant bottles that are nitrogen flushed to ensure freshness.

Sales of products from Manitoba Harvest are spreading fast throughout North America and into Europe, Asia and other regions of the world. The need to create packaging that is appealing to a broad world audience is one of the factors that led Manitoba Harvest to refresh their brand look and packaging. The company’s popular line of Hemp Oil has received a new look and more convenient no-drip spout that is sure to attract the growing throngs of consumers that are seeking out healthy hemp foods. “Our fresh new look is designed to appeal to a broader mainstream audience while providing valuable health and nutrition information,” says Fata.

Manitoba Harvest offers two varieties of hemp oil in a variety of sizes of their attractive new packaging: certified organic (8-ounce SRP $9.99; 16-ounce SRP $16.99) and pesticide-free (12-ounce for $9.99; 32-ounce $23.99). Both varieties contain no additives or preservatives, and they are Gluten-Free and Nut-Free.

Founded in 1998, Manitoba Harvest Hemp Foods & Oils is the world’s largest vertically-integrated, farmer owned hemp food manufacturer. The company strives to create the healthiest hemp foods, to educate the public about healthy lifestyle choices, and to support sustainable and organic agriculture. Manitoba Harvest is proud to partner with Renewable Choice Energy to reduce their environmental impact through wind power and carbon offsets. For more information, please visit www.manitobaharvest.com .

Hempini Dressing
(Makes: 1 1/2 cups; Prep Time: 5 min.)
Ingredients:
1/2 cup Hemp Seed Butter
1/2 Cup Hemp Oil
1/4 Cup Tamari
1/4 Cup Maple Syrup

Directions:
Combine Hemp Oil and Hemp Seed Butter in a bowl. Stir until creamy and smooth. Add tamari and maple syrup. Mix well. Will keep in the refrigerator for 4-5 days in a sealed container. This is a high protein dressing that is ideal for salads, rice or veggies.

Think veggies and dip instead of pizza next time..lol

I cook stuff in boiling water, wait a bit & then inhale it. Why couldn’t cannabis be used this way?

Also never used any …hmm, how to call them.. Let’s say it this way: So far, my only drugs ever were music & love. OK, & religion :) So you will understand, that I’m a bit skeptic or rather say frightened about the vaporizer thing.

As I understand from reading slove sites, there exist 2 sorts of hemp: Eatable hemp (Cannabis sativa or called also “indian”) & “that other” hemp. What’s about it?

I think I'm gonna seed it in my garden. Yeah!

Welcome to www.THC-Foundation.org, The Hemp and Cannabis Foundation

Serving The Cannabis Community Since 1999

Contents Updated Last on 02/07/10

The Hemp & Cannabis Foundation is a 501(c)3 non-profit organization working to truthfully educate the public concerning hemp and cannabis, as well as helping medical marijuana patients. We have clinics across the country where our doctors help patients obtain a permit for medical marijuana.

We have helped over 100,000 patients in nine states obtain a permit to legally possess, use and grow medical marijuana. We would be happy to help you. We are now scheduling appointments in 40 cities across the United States.

We see patients at our clinics in Oregon at Portland, Eugene, Bend, Grants Pass and Umatilla, in Washington state at Seattle/Bellevue, Olympia, Port Angeles, Spokane, Bellingham, Kennewick and Vancouver/Portland, in Michigan at Detroit/Southfield, Grand Rapids, Kalamazoo, Flint, Saginaw, Marquette, Traverse City and Lansing, in Hawaii at Honolulu, Hilo and Kapaa, in Colorado at Denver, Durango and Glenwood Springs, in Nevada at Las Vegas and Reno, in Montana at Missoula, Helena, Bozeman and Billings, in New Mexico at Albuquerque and in California at Riverside.

We are now scheduling appointments for all of our clinics across the United States. Contact us at (800)723-0188 for locations and details.


Under state law in California, Colorado, District of Columbia, Hawaii, Michigan, Montana, Nevada, New Mexico, Oregon, Rhode Island and Washington medical marijuana has helped hundreds of thousands of patients enjoy a better quality of life. Medical marijuana assists many in stopping or reducing habit-forming medications and allows them and their families to lead fuller and more active lives.

All of our physicians are fully licensed, experienced, well informed and compassionate. Our staff explains each state's unique program and helps patients locate community resources so they can best benefit from their state's medical cannabis law.

Our Doctors:

* Thomas Orvald, MD - (Cardiac Surgeon) - Licensed in WA, OR, HI, CO, CA
* Sandra Camacho, MD - (Nuclear Medicine) - Licensed in OR
* David Dodge, MD - (Pathologist) - Licensed in OR
* Rabia Ahmed, MD - (Internal Medicine) - Licensed in OR, CA, HI, NV
* Eric Eisenbud, MD - (Ophthalmologist) - Licensed in CO, MI, MT, WA
* Paul Ironside, MD - (Cardiothoracic Surgeon) - Licensed in CA


Marijuana is much safer, more effective and less costly than many alternatives currently in use. The Drug Enforcement Administration's own top administrative law judge, Francis L. Young, dismissed the drug warriors' untrue propaganda when he ruled in 1988 that, "Marijuana, in its natural form, is one of the safest therapeutically active substances known to man."



Becoming a Patient

Our physicians require that each patient have current medical records that document the existence of one of the conditions for which medical marijuana is authorized under their state law. You must either obtain your medical records yourself (which may involve a fee) and bring them in to us, or you may authorize that your medical records be faxed or mailed to one of our offices. Please BE SURE to clarify with the doctor's office that you only need 2-3 visits of chart notes pertaining to your qualifying condition, NOT your entire medical record. Have them include any relevant x-ray or MRI reports (not actual film), and also YOUR name and phone number.

Since our doctors are consulting with patients solely about their qualification for medicinal cannabis, and can not act as a patient's primary physician, we require that all of our patients have at least one other current physician. What to Expect at Your Appointment

After checking in, we must copy your state identification card for our file, pull your medical records, and create our THCF medical file. You can expect to fill out some questionnaire forms whether you are a new or returning patient. There is a 20 minute orientation video to educate you about your state's medical marijuana program, and then you will have time to ask a staff member any remaining questions you may have. What follows will be a non-invasive exam by an RN or NP, a meeting with our MD who will review your entire situation, make his determination, and fill out necessary forms. Once we both have copies of all necessary information and permit forms filled out, you will be ready to go!